112579

• Gene Symbol: ITGB3
• Gene Name: integrin subunit beta 3
• Gene Aliases: BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT
• Chromosome Location: Chr.17: 47253842 - 47312711 on Build GRCh38
• UniGene ID: Hs.218040
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ITGB3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000212.2	NP_000203.2	10	1293
GenBank mRNA	BC127666.1	-	10	1293	40128462
	BC127667.1	-	10	1297	40128464
	J02703.1	-	10	1293
	KC120777.1	-	10	1293
	KC120778.1	-	10	1293
	M20311.1	-	10	1289
	M35999.1	-	10	1291
	S70348.1	-	2	389
	U95204.1	-	10	1273

More Information

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
platelet degranulation
cell-substrate junction assembly
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
blood coagulation
positive regulation of endothelial cell migration
negative regulation of macrophage derived foam cell differentiation
negative regulation of lipid storage
smooth muscle cell migration
cell growth
cell migration
platelet activation
extracellular matrix organization
positive regulation of vascular endothelial growth factor receptor signaling pathway
cell-substrate adhesion
activation of protein kinase activity
negative regulation of lipid transport
heterotypic cell-cell adhesion
substrate adhesion-dependent cell spreading
tube development
apolipoprotein A-I-mediated signaling pathway
wound healing
regulation of bone resorption
negative regulation of low-density lipoprotein particle receptor biosynthetic process
viral entry into host cell
vascular endothelial growth factor receptor signaling pathway
mesodermal cell differentiation
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of lipoprotein metabolic process
leukocyte migration
negative chemotaxis
angiogenesis involved in wound healing
platelet aggregation

Function(s)

virus receptor activity
fibronectin binding
protease binding
protein disulfide isomerase activity
platelet-derived growth factor receptor binding
protein binding
coreceptor activity
fibroblast growth factor binding
enzyme binding
C-X3-C chemokine binding
insulin-like growth factor I binding
neuregulin binding
identical protein binding
vascular endothelial growth factor receptor 2 binding
cell adhesion molecule binding
extracellular matrix binding