112698

• Gene Symbol: ACE
• Gene Name: angiotensin I converting enzyme
• Gene Aliases: ACE1, CD143, DCP, DCP1, ICH, MVCD3
• Chromosome Location: Chr.17: 63477061 - 63498380 on Build GRCh38
• UniGene ID: Hs.298469
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ACE
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000789.3	NP_000780.1	20, 21	3177
	NM_001178057.1	NP_001171528.1	9, 10	1472
	NM_152830.2	NP_690043.1	9, 10	1472
	XM_006721737.3	XP_006721800.2	9, 10	1585
GenBank mRNA	AB208971.1	-	20, 21	3167
	AK301988.1	-	9, 10	1443
	AK302019.1	-	8, 9	1154
	J04144.1	-	20, 21	3165
	JQ927553.1	-	20, 21	3177
	M26657.1	-	9, 10	1443
	M29981.1	-	9, 10	1521
	X16295.1	-	9, 10	1449

More Information

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

kidney development
blood vessel remodeling
angiotensin maturation
angiotensin catabolic process in blood
regulation of renal output by angiotensin
neutrophil mediated immunity
antigen processing and presentation of peptide antigen via MHC class I
regulation of systemic arterial blood pressure by renin-angiotensin
spermatogenesis
regulation of blood pressure
regulation of smooth muscle cell migration
regulation of vasoconstriction
mononuclear cell proliferation
regulation of vasodilation
hormone catabolic process
peptide catabolic process
beta-amyloid metabolic process
arachidonic acid secretion
heart contraction
regulation of angiotensin metabolic process
hematopoietic stem cell differentiation
positive regulation of protein tyrosine kinase activity
cell proliferation in bone marrow
positive regulation of peptidyl-tyrosine autophosphorylation
regulation of hematopoietic stem cell proliferation
negative regulation of gap junction assembly
positive regulation of peptidyl-cysteine S-nitrosylation

Function(s)

endopeptidase activity
carboxypeptidase activity
drug binding
metallopeptidase activity
exopeptidase activity
tripeptidyl-peptidase activity
peptidyl-dipeptidase activity
zinc ion binding
chloride ion binding
mitogen-activated protein kinase kinase binding
bradykinin receptor binding
mitogen-activated protein kinase binding
metallodipeptidase activity