112974

• Gene Symbol: PSMA6
• Gene Name: proteasome subunit alpha 6
• Gene Aliases: IOTA, PROS27, p27K
• Chromosome Location: Chr.14: 35278558 - 35317479 on Build GRCh38
• UniGene ID: Hs.446260
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSMA6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001282232.1	NP_001269161.1	6	850
	NM_001282233.1	NP_001269162.1	5	707
	NM_001282234.1	NP_001269163.1	6	727
	NM_002791.2	NP_002782.1	6	802
	NR_104110.1		5	623
	XM_017021468.1	XP_016876957.1	6	2138
GenBank mRNA	AK298920.1	-	5	675
	AK302008.1	-	6	652
	AK313011.1	-	6	728
	AK316223.1	-	6	716
	BC002979.1	-	6	693	3542966
	BC017882.1	-	6	715	4278372
	BC022354.1	-	6	672	4292526
	BC023659.1	-	6	720	4869452
	BC070137.1	-	6	724	6458246
	BU198521.1	-	5	497
	CR456944.1	-	6	642
	X59417.1	-	6	704
	X61972.1	-	5	567

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011968, BC086685, AK161662, U60288, AK152915, and others.

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
regulation of inflammatory response
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
proteolysis involved in cellular protein catabolic process
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway

Function(s)

RNA binding
endopeptidase activity
threonine-type endopeptidase activity
protein binding
purine ribonucleoside triphosphate binding
NF-kappaB binding