114053

• Gene Symbol: PITX2
• Gene Name: paired like homeodomain 2
• Gene Aliases: ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS
• Chromosome Location: Chr.4: 110617423 - 110642123 on Build GRCh38
• UniGene ID: Hs.643588
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PITX2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000325.5	NP_000316.2	3	1758
	NM_001204397.1	NP_001191326.1	7	2922
	NM_001204398.1	NP_001191327.1	5	1314
	NM_001204399.1	NP_001191328.1	4	1176
	NM_153426.2	NP_700475.1	6	2688
	NM_153427.2	NP_700476.1	5	2550
	XM_011532027.2	XP_011530329.1	4	2426
GenBank mRNA	AF048720.1	-	4	1211
	AF048721.1	-	5	1349
	AF048722.1	-	3	1713
	AK127829.1	-	7	2760
	AK291591.1	-	4	1204
	BC013998.2	-	3	1757	3937807
	BC106010.1	-	4	1186	3914727
	U69961.1	-	5	1544

More Information

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

patterning of blood vessels
vasculogenesis
in utero embryonic development
neuron migration
extraocular skeletal muscle development
atrioventricular valve development
cardiac neural crest cell migration involved in outflow tract morphogenesis
pulmonary myocardium development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
determination of left/right symmetry
myoblast fusion
male gonad development
female gonad development
response to hormone
Wnt signaling pathway
subthalamic nucleus development
hypothalamus cell migration
regulation of cell migration
embryonic camera-type eye development
response to vitamin A
embryonic hindlimb morphogenesis
hair cell differentiation
vascular smooth muscle cell differentiation
deltoid tuberosity development
odontogenesis of dentin-containing tooth
odontogenesis
camera-type eye development
positive regulation of DNA binding
positive regulation of transcription from RNA polymerase II promoter
spleen development
embryonic digestive tract morphogenesis
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle cell development
somatotropin secreting cell differentiation
prolactin secreting cell differentiation
ventricular septum morphogenesis
left lung morphogenesis
pulmonary vein morphogenesis
superior vena cava morphogenesis
endodermal digestive tract morphogenesis
iris morphogenesis
cell proliferation involved in outflow tract morphogenesis
left/right axis specification
positive regulation of myoblast proliferation

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
RNA polymerase II transcription coactivator activity
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
chromatin DNA binding