11445

• Gene Symbol: LTF
• Gene Name: lactotransferrin
• Gene Aliases: GIG12, HEL110, HLF2, LF
• Chromosome Location: Chr.3: 46436005 - 46485234 on Build GRCh38
• UniGene ID: Hs.529517
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: LTF
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199149.1	NP_001186078.1	2	321
	NM_001321121.1	NP_001308050.1	2	432
	NM_001321122.1	NP_001308051.1	5	665
	NM_002343.5	NP_002334.2	2	432
GenBank mRNA	AK093852.1	-	5	668
	AK290859.1	-	2	177
	AK292813.1	-	2	177
	AK298035.1	-	2	321
	AK303889.1	-	2	177
	AY493417.1	-	2	249
	BC015822.1	-	2	181	4251222
	BC015823.1	-	2	183	4294752
	BP342557.1	-	2	380
	CD722125.1	-	2	165
	EU794669.1	-	2	174
	KT006756.1	-	2	139
	M83202.1	-	2	146
	M83205.1	-	2	125
	U07643.1	-	2	236
	X52941.1	-	2	133
	X53961.1	-	2	433

More Information

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

ossification
regulation of cytokine production
retina homeostasis
innate immune response in mucosa
transcription, DNA-templated
proteolysis
ion transport
humoral immune response
antibacterial humoral response
antifungal humoral response
negative regulation of lipopolysaccharide-mediated signaling pathway
regulation of tumor necrosis factor production
negative regulation of ATPase activity
iron assimilation by chelation and transport
positive regulation of osteoblast proliferation
positive regulation of toll-like receptor 4 signaling pathway
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
cellular protein metabolic process
negative regulation by host of viral process
negative regulation of viral genome replication
cell redox homeostasis
positive regulation of osteoblast differentiation
negative regulation of viral process
positive regulation of NF-kappaB transcription factor activity
bone morphogenesis
positive regulation of protein serine/threonine kinase activity
positive regulation of bone mineralization involved in bone maturation
negative regulation of single-species biofilm formation in or on host organism
positive regulation of chondrocyte proliferation
negative regulation of tumor necrosis factor (ligand) superfamily member 11 production
negative regulation of osteoclast development

Function(s)

DNA binding
serine-type endopeptidase activity
iron ion binding
protein binding
heparin binding
protein serine/threonine kinase activator activity