114529

• Gene Symbol: SIX3
• Gene Name: SIX homeobox 3
• Gene Aliases: HPE2
• Chromosome Location: Chr.2: 44941898 - 44946077 on Build GRCh38
• UniGene ID: Hs.567336
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SIX3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005413.3	NP_005404.1	2	1192
GenBank mRNA	AJ012611.1	-	2	1192
	BF569811.1	-	2	495

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_023990, AB030833.
This siRNA also targets the following transcripts in Mouse: NM_011381, D83145, CD352849, BC098096, X90871.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
eye development
epithelial cell maturation
lens development in camera-type eye
optic vesicle morphogenesis
transcription from RNA polymerase II promoter
brain development
visual perception
proximal/distal axis specification
neuroblast differentiation
telencephalon development
forebrain anterior/posterior pattern specification
forebrain dorsal/ventral pattern formation
cell proliferation in forebrain
telencephalon regionalization
pituitary gland development
negative regulation of Wnt signaling pathway
regulation of cell proliferation
negative regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
circadian behavior
lens induction in camera-type eye
regulation of neural retina development
lens fiber cell differentiation
neuroblast migration
regulation of cell cycle phase transition
regulation of neuroblast proliferation
apoptotic process involved in development
lens fiber cell apoptotic process
regulation of neural precursor cell proliferation

Function(s)

RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription corepressor binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
histone deacetylase binding