114581

• Gene Symbol: SPRY2
• Gene Name: sprouty RTK signaling antagonist 2
• Gene Aliases: IGAN3, hSPRY2
• Chromosome Location: Chr.13: 80335976 - 80341115 on Build GRCh38
• UniGene ID: Hs.18676
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SPRY2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001318536.1	NP_001305465.1	2	452
	NM_001318537.1	NP_001305466.1	2	1128
	NM_001318538.1	NP_001305467.1	2	1022
	NM_005842.3	NP_005833.1	2	695
GenBank mRNA	AF039843.1	-	2	540
	AL713749.1	-	2	1128
	BC004205.2	-	2	306	3533337
	BC015745.1	-	2	256	4863701
	BX648582.1	-	1	2360
	CX866409.1	-	2	695

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001012046, XM_006252438, BC089116.
This siRNA also targets the following transcripts in Mouse: NM_011897, AF176905, BC138768, BC138771, AF153084.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
sensory perception of sound
negative regulation of cell proliferation
positive regulation of gene expression
negative regulation of peptidyl-threonine phosphorylation
negative regulation of cell projection organization
positive regulation of peptidyl-serine phosphorylation
negative regulation of GTPase activity
negative regulation of fibroblast growth factor receptor signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway
inner ear morphogenesis
negative regulation of apoptotic process
negative regulation of MAP kinase activity
cell fate commitment
regulation of cell differentiation
negative regulation of Ras protein signal transduction
negative regulation of neurotrophin TRK receptor signaling pathway
positive regulation of protein kinase B signaling
lung growth
bud elongation involved in lung branching
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of protein serine/threonine kinase activity

Function(s)

protein binding
protein kinase binding
protein serine/threonine kinase inhibitor activity
protein serine/threonine kinase activator activity