115020

• Gene Symbol: CREB1
• Gene Name: cAMP responsive element binding protein 1
• Gene Aliases: CREB, CREB-1
• Chromosome Location: Chr.2: 207529892 - 207605989 on Build GRCh38
• UniGene ID: Hs.516646
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CREB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001320793.1	NP_001307722.1	2	349
	NM_004379.4	NP_004370.1	2	349
	NM_134442.4	NP_604391.1	2	349
	NR_135473.1		2	349
	XM_011510645.1	XP_011508947.1	2	163
	XM_011510646.2	XP_011508948.1	2	325
	XM_011510647.2	XP_011508949.1	2	206
	XM_011510648.2	XP_011508950.1	2	325
	XM_017003399.1	XP_016858888.1	2	299
GenBank mRNA	AK312747.1	-	3	244
	AK315226.1	-	2	140
	AY347527.1	-	2	141
	BC010636.1	-	2	192	3872792
	BC095407.1	-	2	293	30344522
	BT019509.1	-	1	98
	CR407617.1	-	1	98
	DC366797.1	-	2	349
	M27691.1	-	2	214
	M34356.1	-	1	98
	X55545.1	-		241
	X60003.1	-	1	98

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_134443, NM_031017, XM_006245065, XM_006245066, XM_008772050, and others.
This siRNA also targets the following transcripts in Mouse: NM_009952, NM_133828, AK044993, AK044992, AF448507, and others.

Gene Ontology Categories:

Process(es)

response to hypoxia
transcription from RNA polymerase II promoter
protein phosphorylation
signal transduction
transforming growth factor beta receptor signaling pathway
axon guidance
aging
lactation
memory
circadian rhythm
regulation of cell size
visual learning
response to organic substance
negative regulation of transcription by competitive promoter binding
response to activity
viral process
pituitary gland development
positive regulation of transforming growth factor beta3 production
secretory granule organization
response to glucagon
chemotaxis to arachidonic acid
response to nicotine
cellular response to hepatocyte growth factor stimulus
cellular response to platelet-derived growth factor stimulus
response to antidepressant
positive regulation of multicellular organism growth
regulation of circadian rhythm
positive regulation of apoptotic process
positive regulation of fat cell differentiation
positive regulation of osteoclast differentiation
positive regulation of transcription, DNA-templated
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone secretion
positive regulation of lipid biosynthetic process
regulation of fibroblast proliferation
protein stabilization
regulation of glial cell proliferation
lung saccule development
Type I pneumocyte differentiation
cellular response to zinc ion
cellular response to fatty acid
positive regulation of long-term synaptic potentiation
negative regulation of neuron death
response to L-glutamate
cellular response to nerve growth factor stimulus
cellular response to insulin-like growth factor stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription cofactor activity
protein binding
enzyme binding
Hsp70 protein binding
histone acetyltransferase binding
cAMP response element binding
identical protein binding
arrestin family protein binding