115173

• Gene Symbol: RB1
• Gene Name: RB transcriptional corepressor 1
• Gene Aliases: OSRC, PPP1R130, RB, p105-Rb, pRb, pp110
• Chromosome Location: Chr.13: 48303747 - 48481890 on Build GRCh38
• UniGene ID: Hs.408528
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000321.2	NP_000312.2	2	394
GenBank mRNA	AB208788.1	-	2	325
	AK291258.1	-	2	415
	AK299179.1	-	3	305
	AK300284.1	-	3	331
	AK307730.1	-	2	381
	BC039060.1	-	2	380	5142020
	BC040540.1	-	2	390	5267622
	L41870.1	-	2	365
	M15400.1	-	2	366
	M28419.1	-	2	366
	M33647.1	-	2	231

More Information

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

cell cycle checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
chromatin remodeling
transcription, DNA-templated
negative regulation of protein kinase activity
cell cycle arrest
negative regulation of transcription from RNA polymerase II promoter during mitosis
mitotic cell cycle checkpoint
Ras protein signal transduction
regulation of mitotic cell cycle
negative regulation of gene expression
viral process
covalent chromatin modification
androgen receptor signaling pathway
sister chromatid biorientation
neuron projection development
maintenance of mitotic sister chromatid cohesion
glial cell apoptotic process
skeletal muscle cell differentiation
neuron maturation
enucleate erythrocyte differentiation
negative regulation of sequence-specific DNA binding transcription factor activity
regulation of lipid kinase activity
myoblast differentiation
positive regulation of macrophage differentiation
positive regulation of mitotic metaphase/anaphase transition
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
cell morphogenesis involved in neuron differentiation
negative regulation of epithelial cell proliferation
striated muscle cell differentiation
cell division
neuron apoptotic process
protein localization to chromosome, centromeric region
cellular response to xenobiotic stimulus
regulation of cohesin loading
negative regulation of transcription involved in G1/S transition of mitotic cell cycle
regulation of centromere complex assembly
hepatocyte apoptotic process
negative regulation of G1/S transition of mitotic cell cycle
positive regulation of transcription regulatory region DNA binding

Function(s)

core promoter binding
RNA polymerase II activating transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
kinase binding
ubiquitin protein ligase binding
identical protein binding
androgen receptor binding
phosphoprotein binding