115209

• Gene Symbol: FOXO3
• Gene Name: forkhead box O3
• Gene Aliases: AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A
• Chromosome Location: Chr.6: 108559823 - 108684769 on Build GRCh38
• UniGene ID: Hs.220950
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FOXO3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001455.3	NP_001446.1	2	1926
	NM_201559.2	NP_963853.1	3	1899
	XM_005266867.4	XP_005266924.1	3	1147
	XM_005266868.3	XP_005266925.1	2	1171
	XM_011535626.1	XP_011533928.1	2	1097
	XM_011535628.2	XP_011533930.1	2	5455
	XM_011535629.2	XP_011533931.1	2	1120
	XM_017010585.1	XP_016866074.1	3	2832
	XM_017010586.1	XP_016866075.1	2	2715
GenBank mRNA	AF032886.1	-	2	2507
	AJ001589.1	-	2	1643
	AK092357.1	-	3	1287
	AK122861.1	-	3	1482
	AK301304.1	-	2	1088
	AK303933.1	-	2	1072
	AK311587.1	-	2	1186
	BC020227.1	-	3	1887	4111403
	BC021224.2	-	3	1887	4137370
	BC068552.1	-	2	1926	30347471
	CR749261.1	-	2	1156

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ovulation from ovarian follicle
initiation of primordial ovarian follicle growth
antral ovarian follicle growth
oocyte maturation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
regulation of translation
DNA damage response, signal transduction by p53 class mediator
tumor necrosis factor-mediated signaling pathway
cellular response to oxidative stress
glucose homeostasis
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of erythrocyte differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of canonical Wnt signaling pathway
neuronal stem cell population maintenance
extrinsic apoptotic signaling pathway in absence of ligand
regulation of neural precursor cell proliferation
regulation of reactive oxygen species metabolic process

Function(s)

core promoter binding
transcription cofactor binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
beta-catenin binding
protein kinase binding
chromatin DNA binding
sequence-specific DNA binding