115256

• Gene Symbol: HMGB2
• Gene Name: high mobility group box 2
• Gene Aliases: HMG2
• Chromosome Location: Chr.4: 173331376 - 173334444 on Build GRCh38
• UniGene ID: Hs.434953
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HMGB2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001130688.1	NP_001124160.1	3	346
	NM_001130689.1	NP_001124161.1	2	333
	NM_002129.3	NP_002120.1	3	406
GenBank mRNA	AK311864.1	-	3	346
	AU129699.1	-	3	403
	BC000903.2	-	3	298
	BC001063.2	-	3	266	2963045
	BC100019.1	-	3	308	6163784
	BM781845.1	-	2	333
	BT019782.1	-	2	213
	BT019783.1	-	2	213
	X62534.1	-	3	427
	Z17240.1	-	2	144

More Information

Gene Ontology Categories:

Process(es)

positive regulation of endothelial cell proliferation
inflammatory response to antigenic stimulus
DNA topological change
apoptotic DNA fragmentation
chromatin organization
nucleosome assembly
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatid nucleus differentiation
male gonad development
positive regulation of nuclease activity
DNA geometric change
response to lipopolysaccharide
positive regulation of interferon-beta production
V(D)J recombination
response to drug
positive regulation of DNA binding
innate immune response
positive regulation of innate immune response
positive regulation of erythrocyte differentiation
positive regulation of megakaryocyte differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to steroid hormone
regulation of neurogenesis
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
positive chemotaxis
DNA ligation involved in DNA repair
cell chemotaxis
cellular response to lipopolysaccharide
regulation of stem cell proliferation
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

four-way junction DNA binding
enhancer sequence-specific DNA binding
DNA binding
damaged DNA binding
double-stranded DNA binding
single-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
drug binding
DNA binding, bending
protein domain specific binding
chemoattractant activity
transcription regulatory region DNA binding
non-sequence-specific DNA binding, bending
poly(A) RNA binding
RAGE receptor binding
supercoiled DNA binding