115689

• Gene Symbol: NFIB
• Gene Name: nuclear factor I B
• Gene Aliases: CTF, HMGIC/NFIB, NF-I/B, NF1-B, NFI-B, NFI-RED, NFIB2, NFIB3
• Chromosome Location: Chr.9: 14081843 - 14398983 on Build GRCh38
• UniGene ID: Hs.644095
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NFIB
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001190737.1	NP_001177666.1	2	843
	NM_001190738.1	NP_001177667.1	2	738
	NM_005596.3	NP_005587.2	2	843
	XM_005251467.2	XP_005251524.1	2	936
	XM_005251468.4	XP_005251525.1	2	409
	XM_005251469.2	XP_005251526.1	2	936
	XM_005251470.2	XP_005251527.1	2	936
	XM_006716773.2	XP_006716836.1	2	936
	XM_006716774.2	XP_006716837.1	2	936
	XM_006716775.2	XP_006716838.1	2	936
	XM_017014739.1	XP_016870228.1	2	936
	XM_017014740.1	XP_016870229.1	2	754
	XM_017014741.1	XP_016870230.1	2	874
GenBank mRNA	AK131233.1	-	2	738
	AK290603.1	-	2	456
	AK299605.1	-	2	706
	BC001283.1	-	2	466	3462726
	BT007266.1	-	2	308
	BX648845.1	-	2	843
	CD251577.1	-	2	744
	KU178232.1	-	2	308
	KU178233.1	-	2	308
	U07810.1	-	1	252
	U70862.1	-	2	765
	U85193.1	-	2	517

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031566, XM_008763762, XM_006238335, XM_006238336, XM_006238339, and others.
This siRNA also targets the following transcripts in Mouse: NM_001113209, NM_001286131, NM_001113210, NM_008687, NM_001286127, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

chondrocyte differentiation
DNA replication
transcription from RNA polymerase II promoter
glial cell differentiation
principal sensory nucleus of trigeminal nerve development
anterior commissure morphogenesis
hindbrain development
positive regulation of transcription from RNA polymerase II promoter
Clara cell differentiation
Type I pneumocyte differentiation
Type II pneumocyte differentiation
salivary gland cavitation
cell differentiation involved in salivary gland development
lung ciliated cell differentiation
commissural neuron axon guidance
negative regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of mesenchymal cell proliferation involved in lung development
negative regulation of epithelial cell proliferation involved in lung morphogenesis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding