116121

• Gene Symbol: PIAS1
• Gene Name: protein inhibitor of activated STAT 1
• Gene Aliases: DDXBP1, GBP, GU/RH-II, ZMIZ3
• Chromosome Location: Chr.15: 68054179 - 68191464 on Build GRCh38
• UniGene ID: Hs.162458
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PIAS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001320687.1	NP_001307616.1	3	848
	NM_016166.2	NP_057250.1	2	249
	XM_011522126.2	XP_011520428.1	4	956
	XM_011522127.2	XP_011520429.1	2	733
	XM_017022688.1	XP_016878177.1	2	727
	XM_017022689.1	XP_016878178.1	2	740
	XM_017022690.1	XP_016878179.1	2	545
	XM_017022691.1	XP_016878180.1	2	319
GenBank mRNA	AF077951.1	-	2	101
	AF167160.1	-	2	197
	AK094641.1	-	3	848
	AK314515.1	-	2	124
	AY826819.1	-	2	98
	BC053685.1	-	2	102
	BC104646.1	-	2	117
	BC118587.1	-	2	151	40085010
	BC121797.1	-	2	148	40085007
	EF487997.1	-	2	101
	EF487998.1	-	2	101
	FJ997900.1	-	2	101
	U78524.1	-	1	83

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106829, AY644724.
This siRNA also targets the following transcripts in Mouse: NM_019663, AK075708, AF077950, AK153871, BC051417.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
JAK-STAT cascade
protein sumoylation
androgen receptor signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of protein sumoylation
regulation of cell proliferation
fat cell differentiation
positive regulation of transcription, DNA-templated
regulation of interferon-gamma-mediated signaling pathway

Function(s)

DNA binding
transcription coactivator activity
transcription corepressor activity
protein binding
transcription factor binding
zinc ion binding
ligase activity
SUMO transferase activity
enzyme binding
ubiquitin protein ligase binding
androgen receptor binding
SUMO ligase activity