116870

• Gene Symbol: SLC11A1
• Gene Name: solute carrier family 11 member 1
• Gene Aliases: LSH, NRAMP, NRAMP1
• Chromosome Location: Chr.2: 218381766 - 218396894 on Build GRCh38
• UniGene ID: Hs.591607
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SLC11A1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000578.3	NP_000569.3	9	1186
	XM_005246793.3	XP_005246850.1	8	1306
	XM_005246794.3	XP_005246851.1	10	1523
	XM_006712709.3	XP_006712772.1	9	1380
	XM_006712710.3	XP_006712773.1	8	1257
	XM_006712711.3	XP_006712774.1	7	1183
	XM_011511684.2	XP_011509986.1	10	1558
	XM_011511685.2	XP_011509987.1	9	1415
	XM_017004765.1	XP_016860254.1	8	1326
	XM_017004766.1	XP_016860255.1	9	1417
GenBank mRNA	AB209650.1	-	7	2900
	AK298667.1	-	9	940
	AK303398.1	-	9	910
	AK307954.1	-	9	1126
	AK310914.1	-	9	942
	AK311405.1	-	8	793
	BC033754.1	-	7	1192
	BC071165.1	-	10	980	5756382
	D38171.1	-	7	693
	D50402.1	-	9	1021
	D50403.1	-	9	932
	L32185.1	-	9	922

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001031658, XM_006245220, XM_006245219, BC100653.
This siRNA also targets the following transcripts in Mouse: NM_013612, X75355, AK144237, BC109137, AK171343, and others.

Panther Classification:

Molecular Function -

secondary carrier transporter

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
negative regulation of cytokine production
positive regulation of cytokine production
T cell proliferation involved in immune response
T cell cytokine production
positive regulation of dendritic cell antigen processing and presentation
positive regulation of T-helper 1 type immune response
iron ion transport
manganese ion transport
cellular cadmium ion homeostasis
cellular iron ion homeostasis
phagocytosis
inflammatory response
vacuolar acidification
response to bacterium
positive regulation of gene expression
nitrite transport
activation of protein kinase activity
response to lipopolysaccharide
interleukin-2 production
interleukin-3 production
positive regulation of interferon-gamma production
response to interferon-gamma
wound healing
macrophage activation
defense response to bacterium
defense response to protozoan
L-arginine import
MHC class II biosynthetic process
cell redox homeostasis
respiratory burst
positive regulation of transcription from RNA polymerase II promoter
antigen processing and presentation of peptide antigen
mRNA stabilization
positive regulation of phagocytosis
defense response to Gram-negative bacterium
iron ion homeostasis
multicellular organismal iron ion homeostasis
cadmium ion transmembrane transport
divalent metal ion export
manganese ion transmembrane transport

Function(s)

manganese ion transmembrane transporter activity
protein homodimerization activity
transition metal ion transmembrane transporter activity
metal ion:proton antiporter activity