116881

• Gene Symbol: NOS2
• Gene Name: nitric oxide synthase 2
• Gene Aliases: HEP-NOS, INOS, NOS, NOS2A
• Chromosome Location: Chr.17: 27756766 - 27804339 on Build GRCh38
• UniGene ID: Hs.709191
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NOS2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000625.4	NP_000616.3	5	699
	XM_011524859.2	XP_011523161.1	5	725
	XM_011524860.2	XP_011523162.1	4	518
	XM_011524861.1	XP_011523163.1	5	697
GenBank mRNA	AB022318.1	-	4	435
	AF068236.1	-	5	669
	AK304252.1	-	5	697
	BC130283.1	-	5	619	40146314
	BC144126.1	-	5	619	9052646
	D26525.1	-	4	449
	L09210.1	-	5	641
	L24553.1	-	4	511
	S76479.1	-	1	122
	U05810.1	-	5	629
	U20141.1	-	4	435
	U31511.1	-	5	540
	X73029.1	-	5	660

More Information

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

response to hypoxia
positive regulation of leukocyte mediated cytotoxicity
innate immune response in mucosa
arginine catabolic process
superoxide metabolic process
nitric oxide biosynthetic process
nitric oxide mediated signal transduction
circadian rhythm
response to bacterium
negative regulation of gene expression
peptidyl-cysteine S-nitrosylation
positive regulation of guanylate cyclase activity
prostaglandin secretion
cellular response to drug
regulation of cell proliferation
negative regulation of protein catabolic process
defense response to bacterium
regulation of cellular respiration
cell redox homeostasis
negative regulation of blood pressure
positive regulation of vasodilation
regulation of insulin secretion
defense response to Gram-negative bacterium
positive regulation of killing of cells of other organism
oxidation-reduction process
cellular response to lipopolysaccharide
cellular response to interferon-gamma
interleukin-6 secretion
interleukin-8 secretion
regulation of cytokine production involved in inflammatory response

Function(s)

nitric-oxide synthase activity
receptor binding
protein binding
calmodulin binding
FMN binding
heme binding
tetrahydrobiopterin binding
arginine binding
protein homodimerization activity
metal ion binding
flavin adenine dinucleotide binding
NADP binding