117373

• Gene Symbol: RAD50
• Gene Name: RAD50 double strand break repair protein
• Gene Aliases: NBSLD, RAD502, hRad50
• Chromosome Location: Chr.5: 132556924 - 132644621 on Build GRCh38
• UniGene ID: Hs.633509
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RAD50
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005732.3	NP_005723.2	1, 2	537
GenBank mRNA	AF057299.1	-	1, 2	457
	AF057300.1	-	1, 2	457
	AK290597.1	-	1, 2	479
	AK307439.1	-	1, 2	212
	BC062603.1	-	1, 2	454
	BC073850.1	-	1, 2	454
	BC108282.1	-	1, 2	474
	BC136436.1	-	1, 2	429	9020425
	BC140005.1	-	1, 2	531
	DB112912.1	-	1, 2	538
	U63139.1	-	1, 2	524

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022246, AF218576.
This siRNA also targets the following transcripts in Mouse: NM_009012, AK144155, BC058180, U66887, AK018001, and others.

Gene Ontology Categories:

Process(es)

regulation of mitotic recombination
telomere maintenance via recombination
telomere maintenance
double-strand break repair via homologous recombination
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
DNA replication
DNA repair
double-strand break repair
double-strand break repair via nonhomologous end joining
DNA recombination
cellular response to DNA damage stimulus
telomere maintenance via telomerase
reciprocal meiotic recombination
viral process
telomeric 3' overhang formation
positive regulation of protein autophosphorylation
positive regulation of telomere maintenance
DNA duplex unwinding
positive regulation of kinase activity
nucleotide phosphorylation
chromosome organization involved in meiotic cell cycle
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
negative regulation of telomere capping

Function(s)

single-stranded DNA endodeoxyribonuclease activity
DNA binding
double-stranded telomeric DNA binding
ATP-dependent DNA helicase activity
adenylate kinase activity
protein binding
ATP binding
3'-5' exonuclease activity
protein binding, bridging
single-stranded telomeric DNA binding
metal ion binding
G-quadruplex DNA binding