117424

• Gene Symbol: DNMT3B
• Gene Name: DNA methyltransferase 3 beta
• Gene Aliases: ICF, ICF1, M.HsaIIIB
• Chromosome Location: Chr.20: 32762385 - 32809356 on Build GRCh38
• UniGene ID: Hs.643024
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DNMT3B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001207055.1	NP_001193984.1	16	2099
	NM_001207056.1	NP_001193985.1	15	1997
	NM_006892.3	NP_008823.1	18	2285
	NM_175848.1	NP_787044.1	17	2225
	NM_175849.1	NP_787045.1	17	2225
	NM_175850.2	NP_787046.1	17	2204
	XM_011528653.2	XP_011526955.1	17	2077
	XM_011528654.2	XP_011526956.1	16	1952
GenBank mRNA	AB208880.1	-	17	2449
	AF129267.1	-	1	59
	AF129268.1	-	1	59
	AF129269.1	-	1	59
	AF156487.1	-	17	2018
	AF156488.1	-	18	2078
	AF176228.1	-	17	2204
	AF331857.1	-	18	2285
	AK001191.1	-	11	1157
	AK295176.1	-	15	1699
	AK299915.1	-	16	1876
	DQ321787.1	-	17	2319

More Information

Panther Classification:

Molecular Function -

DNA methyltransferase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
DNA methylation
response to toxic substance
response to ionizing radiation
DNA methylation on cytosine within a CG sequence
positive regulation of gene expression
response to activity
response to caffeine
response to estradiol
response to vitamin A
response to cocaine
response to drug
positive regulation of neuron differentiation
negative regulation of gene expression, epigenetic
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
positive regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
cellular response to hyperoxia
cellular response to dexamethasone stimulus
C-5 methylation of cytosine

Function(s)

chromatin binding
transcription corepressor activity
DNA (cytosine-5-)-methyltransferase activity
protein binding
DNA-methyltransferase activity
histone deacetylase binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates