11835

• Gene Symbol: FURIN
• Gene Name: furin, paired basic amino acid cleaving enzyme
• Gene Aliases: FUR, PACE, PCSK3, SPC1
• Chromosome Location: Chr.15: 90868592 - 90883458 on Build GRCh38
• UniGene ID: Hs.513153
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FURIN
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001289823.1	NP_001276752.1	16	2585
	NM_001289824.1	NP_001276753.1	16	2739
	NM_002569.3	NP_002560.1	16	2638
GenBank mRNA	BC012181.1	-	15	2408	4550620
	X17094.1	-	16	2575

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019331, XM_008759556, XM_008759555, X55660.

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

signal peptide processing
transforming growth factor beta receptor signaling pathway
aging
cell proliferation
negative regulation of endopeptidase activity
protein processing
peptide hormone processing
viral life cycle
viral protein processing
extracellular matrix disassembly
extracellular matrix organization
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
collagen catabolic process
nerve growth factor processing
negative regulation of low-density lipoprotein particle receptor catabolic process
nerve growth factor production
negative regulation of nerve growth factor production
negative regulation of transforming growth factor beta1 production
secretion by cell
regulation of protein catabolic process
peptide biosynthetic process
cellular protein metabolic process
regulation of low-density lipoprotein particle receptor biosynthetic process
positive regulation of membrane protein ectodomain proteolysis
regulation of endopeptidase activity

Function(s)

protease binding
endopeptidase activity
serine-type endopeptidase activity
serine-type endopeptidase inhibitor activity
protein binding
peptidase activity
peptide binding
metal ion binding
nerve growth factor binding