118737

• Gene Symbol: CDK5
• Gene Name: cyclin dependent kinase 5
• Gene Aliases: LIS7, PSSALRE
• Chromosome Location: Chr.7: 151053812 - 151057965 on Build GRCh38
• UniGene ID: Hs.647078
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CDK5
Interrogated Sequence		Translated Protein	RNADB ID	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001164410.2	NP_001157882.1		9, 10	725
	NM_004935.3	NP_004926.1		10, 11	821
GenBank mRNA	AK026533.1	-		10, 11	742
	AY049778.1	-		10, 11	704
	AY927560.1	-	LIT3563 AY927560	5, 6	743
	BC005115.1	-		10, 11	729	3537202
	BT006680.1	-		10, 11	704
	CR457041.1	-		10, 11	704
	DQ411039.1	-		9, 10	608
	KU177968.1	-		10, 11	704
	KU177969.1	-		9, 10	608
	L04658.1	-		10, 11	716
	X66364.1	-		10, 11	728

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_007668, BC052007, AK216613, AK051790, D29678.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

neuron migration
synaptic transmission, dopaminergic
intracellular protein transport
nucleocytoplasmic transport
cell cycle
cell-matrix adhesion
chemical synaptic transmission
synapse assembly
skeletal muscle tissue development
motor neuron axon guidance
cell proliferation
visual learning
response to wounding
Schwann cell development
synaptic vesicle exocytosis
regulation of macroautophagy
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
sensory perception of pain
cerebellar cortex formation
hippocampus development
layer formation in cerebral cortex
central nervous system neuron development
corpus callosum development
neuron differentiation
regulation of cell migration
negative regulation of axon extension
cortical actin cytoskeleton organization
neuron projection development
negative regulation of protein ubiquitination
negative regulation of synaptic plasticity
positive regulation of protein binding
receptor catabolic process
serine phosphorylation of STAT3 protein
synaptic transmission, glutamatergic
protein localization to synapse
regulation of apoptotic process
receptor clustering
positive regulation of neuron apoptotic process
negative regulation of cell cycle
positive regulation of protein kinase activity
negative regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of calcium ion-dependent exocytosis
protein autophosphorylation
negative regulation of protein export from nucleus
behavioral response to cocaine
regulation of synaptic plasticity
synaptic vesicle endocytosis
rhythmic process
axon extension
oligodendrocyte differentiation
dendrite morphogenesis
cell division
neuron apoptotic process
excitatory postsynaptic potential
regulation of dendritic spine morphogenesis
calcium ion import
regulation of cell cycle arrest
positive regulation of protein targeting to membrane
negative regulation of neuron death
regulation of signal transduction by p53 class mediator
regulation of synaptic vesicle recycling
positive regulation of actin cytoskeleton reorganization
positive regulation of receptor activity

Function(s)

p53 binding
protein kinase activity
protein serine/threonine kinase activity
cyclin-dependent protein serine/threonine kinase activity
ErbB-2 class receptor binding
protein binding
ATP binding
cytoskeletal protein binding
kinase activity
protein kinase binding
acetylcholine receptor activator activity
ErbB-3 class receptor binding
ephrin receptor binding
tau-protein kinase activity