119428 Validated

• Gene Symbol: SOD1
• Gene Name: superoxide dismutase 1, soluble
• Gene Aliases: ALS, ALS1, HEL-S-44, IPOA, SOD, hSod1, homodimer
• Chromosome Location: Chr.21: 31659622 - 31668931 on Build GRCh38
• UniGene ID: Hs.443914
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SOD1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000454.4	NP_000445.1	2	280
GenBank mRNA	AK312116.1	-	2	211
	AV756797.1	-	2	304
	AY049787.1	-	2	132
	AY450286.1	-	2	132
	BC001034.1	-	2	199	3140145
	BT006676.1	-	2	132
	CR450355.1	-	2	132
	CR541742.1	-	2	132
	EF151142.1	-	2	189
	EU794661.1	-	2	189
	W17182.1	-	2	279
	X02317.1	-	2	196

More Information

Matching Taqman Gene Expression Assay:

Hs00166575_m1

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

activation of MAPK activity
response to reactive oxygen species
response to superoxide
ovarian follicle development
positive regulation of cytokine production
placenta development
retina homeostasis
response to amphetamine
myeloid cell homeostasis
platelet degranulation
glutathione metabolic process
superoxide metabolic process
cellular iron ion homeostasis
spermatogenesis
embryo implantation
cell aging
sensory perception of sound
locomotory behavior
anterograde axonal transport
retrograde axonal transport
regulation of blood pressure
response to heat
response to organic substance
transmission of nerve impulse
removal of superoxide radicals
response to nutrient levels
peripheral nervous system myelin maintenance
positive regulation of superoxide anion generation
regulation of T cell differentiation in thymus
response to carbon monoxide
cellular response to potassium ion
regulation of multicellular organism growth
response to drug
response to hydrogen peroxide
superoxide anion generation
positive regulation of apoptotic process
positive regulation of catalytic activity
regulation of GTPase activity
negative regulation of neuron apoptotic process
response to ethanol
negative regulation of cholesterol biosynthetic process
regulation of protein kinase activity
regulation of organ growth
response to antibiotic
response to copper ion
muscle cell cellular homeostasis
thymus development
response to axon injury
hydrogen peroxide biosynthetic process
regulation of mitochondrial membrane potential
oxidation-reduction process
heart contraction
neurofilament cytoskeleton organization
relaxation of vascular smooth muscle
auditory receptor cell stereocilium organization
cellular response to cadmium ion
cellular response to ATP
reactive oxygen species metabolic process
response to antipsychotic drug
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Function(s)

superoxide dismutase activity
copper ion binding
protein binding
zinc ion binding
protein phosphatase 2B binding
identical protein binding
protein homodimerization activity
Rac GTPase binding
chaperone binding