119580 Validated

• Gene Symbol: ADAR
• Gene Name: adenosine deaminase, RNA specific
• Gene Aliases: ADAR1, AGS6, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88DSRBP, P136
• Chromosome Location: Chr.1: 154582057 - 154628016 on Build GRCh38
• UniGene ID: Hs.12341
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ADAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001025107.2	NP_001020278.1	2	279
	NM_001111.4	NP_001102.2	2	410
	NM_001193495.1	NP_001180424.1	2	448
	NM_015840.3	NP_056655.2	2	410
	NM_015841.3	NP_056656.2	2	410
	XM_006711109.2	XP_006711172.1	2	216
	XM_006711111.3	XP_006711174.1	2	474
	XM_006711112.2	XP_006711175.1	2	176
	XM_006711113.2	XP_006711176.1	2	250
	XM_011509060.1	XP_011507362.1	2	312
	XM_011509061.2	XP_011507363.2	2	279
	XM_011509062.1	XP_011507364.1	2	239
	XM_017000037.1	XP_016855526.1	2	343
GenBank mRNA	AA449679.1	-	2	195
	AB209891.1	-	2	223
	AK097241.1	-	2	186
	BC038227.1	-	2	337	5497548
	BX538232.1	-	2	263
	BX640741.1	-	2	261
	CR982397.1	-	2	410
	DA507408.1	-	2	280
	EF190448.1	-	2	177
	EF190449.1	-	2	177
	EF190450.1	-	1	156
	EF190451.1	-	1	156
	EF190452.1	-	1	168
	KJ544856.1	-	1	168
	U10439.1	-	2	322
	U18121.1	-	2	215
	X98559.1	-	1	153

More Information

Matching Taqman Gene Expression Assay:

Hs00241666_m1

Panther Classification:

Molecular Function -

RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

osteoblast differentiation
in utero embryonic development
hematopoietic progenitor cell differentiation
somatic diversification of immune receptors via somatic mutation
adenosine to inosine editing
mRNA processing
response to virus
base conversion or substitution editing
erythrocyte differentiation
pre-miRNA processing
miRNA loading onto RISC involved in gene silencing by miRNA
response to interferon-alpha
negative regulation of apoptotic process
negative regulation of protein kinase activity by regulation of protein phosphorylation
positive regulation of viral genome replication
negative regulation of viral genome replication
innate immune response
defense response to virus
definitive hemopoiesis
type I interferon signaling pathway
negative regulation of type I interferon-mediated signaling pathway
hematopoietic stem cell homeostasis
cellular response to virus
negative regulation of RNA interference

Function(s)

DNA binding
double-stranded RNA adenosine deaminase activity
protein binding
poly(A) RNA binding
metal ion binding