120208 Validated

• Gene Symbol: HDAC2
• Gene Name: histone deacetylase 2
• Gene Aliases: HD2, RPD3, YAF1
• Chromosome Location: Chr.6: 113936156 - 113971195 on Build GRCh38
• UniGene ID: Hs.3352
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HDAC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001527.3	NP_001518.3	3	473
	NR_033441.1		4	501
	NR_073443.1		3	379
	XM_011535788.1	XP_011534090.1	4	225
	XM_017010799.1	XP_016866288.1	4	447
GenBank mRNA	AK092156.1	-	3	379
	AK097376.1	-	4	435
	AK296856.1	-	3	473
	BC031055.1	-	3	437
	BP201509.1	-	3	468
	U31814.1	-	3	390

More Information

Matching Taqman Gene Expression Assay:

Hs00231032_m1

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to amphetamine
cardiac muscle hypertrophy
chromatin remodeling
maintenance of chromatin silencing
transcription, DNA-templated
blood coagulation
positive regulation of cell proliferation
epidermal cell differentiation
positive regulation of epithelial to mesenchymal transition
positive regulation of receptor biosynthetic process
negative regulation of neuron projection development
dendrite development
histone deacetylation
response to caffeine
response to lipopolysaccharide
positive regulation of interleukin-1 production
positive regulation of tumor necrosis factor production
circadian regulation of gene expression
positive regulation of collagen biosynthetic process
cellular response to heat
response to nicotine
response to cocaine
odontogenesis of dentin-containing tooth
response to drug
positive regulation of tyrosine phosphorylation of Stat3 protein
embryonic digit morphogenesis
ATP-dependent chromatin remodeling
negative regulation of apoptotic process
negative regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of MHC class II biosynthetic process
positive regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
behavioral response to ethanol
positive regulation of oligodendrocyte differentiation
response to hyperoxia
hair follicle placode formation
negative regulation of dendritic spine development
eyelid development in camera-type eye
fungiform papilla formation
cellular response to hydrogen peroxide
histone H3 deacetylation
histone H4 deacetylation
cellular response to retinoic acid
cellular response to transforming growth factor beta stimulus
regulation of signal transduction by p53 class mediator
cellular response to dopamine
negative regulation of peptidyl-lysine acetylation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
core promoter binding
RNA polymerase II repressing transcription factor binding
chromatin binding
histone deacetylase activity
protein binding
transcription factor binding
deacetylase activity
enzyme binding
heat shock protein binding
nucleosomal DNA binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
sequence-specific DNA binding
poly(A) RNA binding
NF-kappaB binding