12021

• Gene Symbol: HTRA1
• Gene Name: HtrA serine peptidase 1
• Gene Aliases: ARMD7, CADASIL2, CARASIL, HtrA, L56, ORF480, PRSS11
• Chromosome Location: Chr.10: 122461525 - 122514908 on Build GRCh38
• UniGene ID: Hs.501280
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HTRA1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002775.4	NP_002766.1	2	613
GenBank mRNA	AF097709.1	-	2	56
	AK091944.1	-	4	388
	AK092476.1	-	3	394
	BC011352.1	-	3	380
	BC031082.1	-	2	521
	D87258.1	-	2	533
	DA633502.1	-	4	388
	Y07921.1	-	2	523

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031721, BC081767, AF179370.
This siRNA also targets the following transcripts in Mouse: NM_019564, AF179369, BC013516, AF172994, AK128916, and others.

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

regulation of cell growth
placenta development
proteolysis
extracellular matrix disassembly
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
positive regulation of epithelial cell proliferation
negative regulation of defense response to virus
chorionic trophoblast cell differentiation
dentinogenesis

Function(s)

serine-type endopeptidase activity
insulin-like growth factor binding
serine-type peptidase activity