120254 Validated

• Gene Symbol: PSMC2
• Gene Name: proteasome 26S subunit, ATPase 2
• Gene Aliases: MSS1, Nbla10058, S7
• Chromosome Location: Chr.7: 103344405 - 103369395 on Build GRCh38
• UniGene ID: Hs.437366
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSMC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001204453.1	NP_001191382.1	5	517
	NM_002803.3	NP_002794.1	5	517
	XM_005250505.1	XP_005250562.1	6	638
GenBank mRNA	AB075520.1	-	5	378
	AK298529.1	-	5	365
	AK298821.1	-	4	278
	AK312648.1	-	5	369
	BC002589.2	-	5	361	3161790
	BM754312.1	-	5	399
	D11094.1	-	5	395

More Information

Matching Taqman Gene Expression Assay:

Hs00792473_m1

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

MAPK cascade
protein polyubiquitination
osteoblast differentiation
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
ubiquitin-dependent protein catabolic process
regulation of cellular amino acid metabolic process
viral process
ER-associated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of proteasomal protein catabolic process

Function(s)

protein binding
ATP binding
ATPase activity
TBP-class protein binding
proteasome-activating ATPase activity