120436

• Gene Symbol: RASGRP1
• Gene Name: RAS guanyl releasing protein 1
• Gene Aliases: CALDAG-GEFI, CALDAG-GEFII, RASGRP, V, hRasGRP1
• Chromosome Location: Chr.15: 38488097 - 38564806 on Build GRCh38
• UniGene ID: Hs.591127
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RASGRP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001128602.1	NP_001122074.1	5	620
	NM_001306086.1	NP_001293015.1	5	620
	NM_005739.3	NP_005730.2	5	620
	XM_005254114.2	XP_005254171.1	5	609
	XM_011521151.2	XP_011519453.1	5	609
	XM_017021860.1	XP_016877349.1	5	547
GenBank mRNA	AF081195.1	-	5	545
	AF081197.1	-	4	399
	AF106071.1	-	5	454
	AK295097.1	-	4	484
	AK314091.1	-	5	620
	AK316067.1	-	5	548
	AY634315.2	-	5	449
	AY858556.2	-	5	449
	AY954625.4	-	5	449
	AY966005.1	-	5	449
	BC067298.1	-	5	525
	BC109296.1	-	5	492	40034427
	BC109297.1	-	5	492	40034428

More Information

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

MAPK cascade
cytokine production
positive regulation of protein phosphorylation
inflammatory response to antigenic stimulus
signal transduction
Ras protein signal transduction
regulation of phosphatidylinositol 3-kinase signaling
cell differentiation
secretory granule localization
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of tumor necrosis factor production
positive regulation of natural killer cell differentiation
positive regulation of T cell differentiation in thymus
mast cell degranulation
positive regulation of MAP kinase activity
positive regulation of GTPase activity
positive regulation of natural killer cell mediated cytotoxicity
positive regulation of JNK cascade
positive regulation of Ras protein signal transduction
vesicle transport along microtubule
protein oligomerization
regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
activation of GTPase activity
regulation of phospholipase C activity
regulation of p38MAPK cascade
positive regulation of interferon-gamma secretion

Function(s)

phosphatidylserine binding
guanyl-nucleotide exchange factor activity
Ras guanyl-nucleotide exchange factor activity
calcium ion binding
zinc ion binding
lipid binding
diacylglycerol binding
phosphatidylcholine binding
protein homodimerization activity