120642 Validated

• Gene Symbol: MCL1
• Gene Name: BCL2 family apoptosis regulator
• Gene Aliases: BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
• Chromosome Location: Chr.1: 150574551 - 150579738 on Build GRCh38
• UniGene ID: Hs.632486
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MCL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001197320.1	NP_001184249.1	4	784
	NM_021960.4	NP_068779.1	3	1243
	NM_182763.2	NP_877495.1	2	995
GenBank mRNA	AF118124.1	-	3	1084
	AF203373.1	-	2	787
	AK294462.1	-	4	815
	AK297217.1	-	4	779
	AK300499.1	-	4	889
	AK304775.1	-	4	925
	AK312508.1	-	3	1115
	AK316267.1	-	4	1071
	BC017197.2	-	3	1089	3138465
	BC071897.1	-	3	1091	6586159
	BC107735.1	-	3	1106	4770487
	BT006640.1	-	3	1035
	FJ917536.1	-	4	576
	L08246.1	-	3	1095

More Information

Matching Taqman Gene Expression Assay:

Hs00172036_m1

Gene Ontology Categories:

Process(es)

cell fate determination
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cellular homeostasis
response to cytokine
negative regulation of apoptotic process
protein transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein channel activity
protein homodimerization activity
protein heterodimerization activity
BH3 domain binding