120716

• Gene Symbol: BCL2L1
• Gene Name: BCL2 like 1
• Gene Aliases: BCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52
• Chromosome Location: Chr.20: 31664452 - 31723999 on Build GRCh38
• UniGene ID: Hs.516966
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BCL2L1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001191.3	NP_001182.1	2	687
	NM_001317919.1	NP_001304848.1	2	669
	NM_001317920.1	NP_001304849.1	2	324
	NM_001317921.1	NP_001304850.1	2	453
	NM_001322239.1	NP_001309168.1	2	342
	NM_001322240.1	NP_001309169.1	2	471
	NM_001322242.1	NP_001309171.1	2	324
	NM_138578.2	NP_612815.1	2	687
	NR_134257.1		1	188
	XM_011528964.2	XP_011527266.1	2	306
	XM_017027993.1	XP_016883482.1	2	312
GenBank mRNA	AK290968.1	-	2	457
	BC019307.1	-	2	442	2823498
	BM554265.1	-	2	426
	BT007208.1	-	1	76
	BX359456.2	-	2	359
	CR936637.1	-	2	473
	DR156871.1	-	2	233
	KU177938.1	-	1	76
	KU177939.1	-	1	76
	KU177940.1	-	1	76
	Z23115.1	-	1	210
	Z23116.1	-	1	210

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001289716, NM_009743, NM_001289739, NM_001289717, U10102, and others.

Gene Ontology Categories:

Process(es)

cytokinesis
ovarian follicle development
in utero embryonic development
release of cytochrome c from mitochondria
endocytosis
mitotic cell cycle checkpoint
germ cell development
spermatogenesis
cell proliferation
positive regulation of cell proliferation
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
fertilization
suppression by virus of host apoptotic process
response to cytokine
growth
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
response to cycloheximide
regulation of mitochondrial membrane permeability
neuron apoptotic process
regulation of mitochondrial membrane potential
cellular process regulating host cell cycle in response to virus
mitochondrion morphogenesis
cellular response to amino acid stimulus
cellular response to alkaloid
cellular response to gamma radiation
apoptotic process in bone marrow
negative regulation of establishment of protein localization to plasma membrane
negative regulation of release of cytochrome c from mitochondria
extrinsic apoptotic signaling pathway in absence of ligand
hepatocyte apoptotic process
negative regulation of execution phase of apoptosis
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein kinase binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
BH3 domain binding