120793

• Gene Symbol: PSMC1
• Gene Name: proteasome 26S subunit, ATPase 1
• Gene Aliases: P26S4, S4, p56
• Chromosome Location: Chr.14: 90256550 - 90272625 on Build GRCh38
• UniGene ID: Hs.356654
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSMC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002802.2	NP_002793.2	4	264
	XM_017021470.1	XP_016876959.1	4	1783
	XM_017021471.1	XP_016876960.1	5	340
GenBank mRNA	AB451311.1	-	1	216
	AB451441.1	-	1	216
	AK222668.1	-	4	232
	AK299121.1	-	3	140
	AK313325.1	-	4	253
	BC000512.2	-	1	250	2822718
	BC016368.1	-	1	244	4133348
	BC018859.2	-	1	217
	BC073818.1	-	1	222	5456334
	BT009826.1	-	1	216
	CR457044.1	-	1	216
	L02426.1	-	4	276

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_057123, BC063157, D50696, FQ209916.
This siRNA also targets the following transcripts in Mouse: NM_008947, BC003860, AK169015, U39302, AK166783, and others.

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
ER-associated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
negative regulation of neuron death
positive regulation of proteasomal protein catabolic process

Function(s)

protein binding
ATP binding
ATPase activity
TBP-class protein binding
proteasome-activating ATPase activity
poly(A) RNA binding