121279

• Gene Symbol: ANGPT1
• Gene Name: angiopoietin 1
• Gene Aliases: AGP1, AGPT, ANG1
• Chromosome Location: Chr.8: 107249482 - 107498055 on Build GRCh38
• UniGene ID: Hs.369675
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ANGPT1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001146.4	NP_001137.2	1	607
	NM_001199859.2	NP_001186788.1	1	607
GenBank mRNA	AB084454.1	-	1	110
	AK304717.1	-	1	60
	AY121504.1	-	1	110
	AY124380.1	-	1	110
	BC152411.1	-	1	461	8862514
	BC152419.1	-	1	473	8862529
	BX648814.1	-	1	608
	D13628.2	-	1	461
	U83508.1	-	1	419

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009640, NM_001286062, AK012027, AK088439, AK172868, and others.

Panther Classification:

Molecular Function -

intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
in utero embryonic development
negative regulation of protein phosphorylation
regulation of endothelial cell proliferation
sprouting angiogenesis
positive regulation of receptor internalization
negative regulation of cytokine secretion involved in immune response
negative regulation of cell adhesion
activation of transmembrane receptor protein tyrosine kinase activity
positive regulation of endothelial cell migration
positive regulation of phosphatidylinositol 3-kinase signaling
regulation of skeletal muscle satellite cell proliferation
hemopoiesis
cell differentiation
heparin biosynthetic process
positive regulation of protein ubiquitination
cell-substrate adhesion
regulation of tumor necrosis factor production
positive regulation of peptidyl-serine phosphorylation
protein localization to cell surface
negative regulation of protein import into nucleus
negative regulation of apoptotic process
negative regulation of vascular permeability
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of protein binding
negative regulation of neuron apoptotic process
positive regulation of blood vessel endothelial cell migration
positive regulation of GTPase activity
positive regulation of cell adhesion
Tie signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation
leukocyte migration
positive chemotaxis
positive regulation of protein kinase B signaling
positive regulation of ERK1 and ERK2 cascade
glomerulus vasculature development
negative regulation of endothelial cell apoptotic process
regulation of macrophage migration inhibitory factor signaling pathway

Function(s)

Ras guanyl-nucleotide exchange factor activity
receptor tyrosine kinase binding