121387

• Gene Symbol: NTHL1
• Gene Name: nth-like DNA glycosylase 1
• Gene Aliases: FAP3, NTH1, OCTS3, hNTH1
• Chromosome Location: Chr.16: 2039815 - 2047872 on Build GRCh38
• UniGene ID: Hs.66196
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NTHL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001318193.1	NP_001305122.1	2, 3	410
	NM_001318194.1	NP_001305123.1	3, 4	429
	NM_002528.6	NP_002519.1	3, 4	581
	XM_017023253.1	XP_016878742.1	3, 4	584
GenBank mRNA	AB001575.1	-	3, 4	545
	BC000391.2	-	3, 4	538
	BC003014.1	-	3, 4	538	2821314
	BE900738.1	-	2, 3	292
	BG468617.1	-	3, 4	355
	U79718.1	-	3, 4	578
	U81285.1	-	3, 4	543
	Y09687.1	-	3, 4	532

More Information

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
base-excision repair, AP site formation
nucleotide-excision repair, DNA incision, 5'-to lesion
depyrimidination
mitophagy in response to mitochondrial depolarization
xenophagy

Function(s)

oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
double-stranded DNA binding
DNA-(apurinic or apyrimidinic site) lyase activity
endonuclease activity
protein binding
oxidized purine nucleobase lesion DNA N-glycosylase activity
DNA N-glycosylase activity
metal ion binding
4 iron, 4 sulfur cluster binding