121540

Gene Symbol:

ARHGEF5 ARHGEF34P

Gene Name:

Rho guanine nucleotide exchange factor 5

Rho guanine nucleotide exchange factor 34, pseudogene

Gene Aliases:

GEF5, P60, TIM, TIM1

-

Chromosome Location:

Chr.7: 144355341 - 144380632 on Build GRCh38

Chromosome Location:

Chr.7: 144258996 - 144286003 on Build GRCh38

UniGene ID:

Hs.334

Hs.744262

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: ARHGEF5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005435.3	NP_005426.2	12	4494
GenBank mRNA	AK123596.1	-	11	2693
	AK160365.1	-	12	4550
	BC010046.2	-	12	1439
	BC011839.2	-	12	1439
	BC014555.2	-	12	1439
	BC136661.1	-	12	4408	9020651
	BX649178.1	-	11	2379
	CR749203.1	-	12	4434
	U02082.1	-	10	1235

Gene Symbol: ARHGEF34P
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_033942.1		11	3412
GenBank mRNA	BC107871.1	-	5	433
	DQ786236.1	-	6	549
	DQ786285.1	-	2	146

More Information

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

myeloid dendritic cell chemotaxis
actin cytoskeleton organization
regulation of actin cytoskeleton organization
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of GTPase activity
positive regulation of JUN kinase activity
positive regulation of GTPase activity
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
positive regulation of stress fiber assembly
regulation of ERK1 and ERK2 cascade
positive regulation of podosome assembly
positive regulation of protein import

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
GTP binding
lipid binding