121591

• Gene Symbol: TNFAIP3
• Gene Name: TNF alpha induced protein 3
• Gene Aliases: A20, AISBL, OTUD7C, TNFA1P2
• Chromosome Location: Chr.6: 137866317 - 137883314 on Build GRCh38
• UniGene ID: Hs.211600
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFAIP3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001270507.1	NP_001257436.1	5, 6	1146
	NM_001270508.1	NP_001257437.1	5, 6	1170
	NM_006290.3	NP_006281.1	5, 6	1122
	XM_005267119.1	XP_005267176.1	5, 6	889
	XM_006715555.1	XP_006715618.1	3, 4	627
	XM_011536095.1	XP_011534397.1	6, 7	1165
	XM_011536096.1	XP_011534398.1	5, 6	1150
GenBank mRNA	AK312862.1	-	5, 6	1074
	AL157444.1	-	3, 4	338
	BC113871.1	-	4, 5	823	40036694
	BC114480.1	-	4, 5	823	40036692
	FJ434405.1	-	4, 5	800
	FJ434406.1	-	4, 5	800
	FJ434408.1	-	4, 5	800
	FJ434409.1	-	4, 5	800
	FJ434410.1	-		800
	FJ434411.1	-	4, 5	800
	FJ434412.1	-	4, 5	800
	FJ434413.1	-	4, 5	800
	FJ434414.1	-	4, 5	800
	M59465.1	-	5, 6	866

More Information

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

B-1 B cell homeostasis
response to molecule of bacterial origin
regulation of germinal center formation
negative regulation of chronic inflammatory response
apoptotic process
inflammatory response
regulation of tumor necrosis factor-mediated signaling pathway
protein deubiquitination
negative regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
negative regulation of type I interferon production
response to muramyl dipeptide
negative regulation of interleukin-1 beta production
negative regulation of interleukin-2 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
negative regulation of toll-like receptor 2 signaling pathway
negative regulation of toll-like receptor 3 signaling pathway
negative regulation of toll-like receptor 4 signaling pathway
negative regulation of toll-like receptor 5 signaling pathway
protein K11-linked deubiquitination
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of bone resorption
negative regulation of innate immune response
negative regulation of smooth muscle cell proliferation
regulation of defense response to virus by host
regulation of inflammatory response
negative regulation of inflammatory response
negative regulation of B cell activation
protein oligomerization
regulation of vascular wound healing
cellular response to hydrogen peroxide
nucleotide-binding oligomerization domain containing signaling pathway
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
protein K63-linked deubiquitination
protein K48-linked ubiquitination
protein K48-linked deubiquitination
cellular response to lipopolysaccharide
protein deubiquitination involved in ubiquitin-dependent protein catabolic process
tolerance induction to lipopolysaccharide
establishment of protein localization to vacuole
negative regulation of osteoclast proliferation
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of cellular protein catabolic process
positive regulation of hepatocyte proliferation
negative regulation of CD40 signaling pathway
negative regulation of endothelial cell apoptotic process

Function(s)

protease binding
DNA binding
ubiquitin-protein transferase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
zinc ion binding
ligase activity
kinase binding
ubiquitin binding
protein self-association
K63-linked polyubiquitin binding