122145

• Gene Symbol: SFRP2
• Gene Name: secreted frizzled related protein 2
• Gene Aliases: FRP-2, SARP1, SDF-5
• Chromosome Location: Chr.4: 153780590 - 153789076 on Build GRCh38
• UniGene ID: Hs.481022
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SFRP2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003013.2	NP_003004.1	1, 2	747
GenBank mRNA	AF017986.1	-	1, 2	764
	AF311912.1	-	1, 2	743
	AK075372.1	-	1, 2	740
	AK093922.1	-	2, 3	715
	AY359001.1	-	1, 2	549
	BC008666.1	-	1, 2	727	3874262
	BM924815.1	-	1, 2	763

More Information

• Set Membership: G-protein coupled receptor

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

patterning of blood vessels
chondrocyte development
outflow tract morphogenesis
cardiac left ventricle morphogenesis
apoptotic process
G-protein coupled receptor signaling pathway
cell-cell signaling
response to nutrient
positive regulation of cell proliferation
negative regulation of cell proliferation
male gonad development
negative regulation of gene expression
negative regulation of cardiac muscle cell apoptotic process
negative regulation of epithelial to mesenchymal transition
positive regulation of endopeptidase activity
negative regulation of Wnt signaling pathway
collagen fibril organization
positive regulation of cell growth
negative regulation of cell growth
negative regulation of cell migration
negative regulation of BMP signaling pathway
cellular response to extracellular stimulus
positive regulation of peptidyl-serine phosphorylation
positive regulation of cell adhesion mediated by integrin
positive regulation of catenin import into nucleus
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
response to drug
negative regulation of mesodermal cell fate specification
embryonic digit morphogenesis
positive regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of JUN kinase activity
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
positive regulation of angiogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
digestive tract morphogenesis
negative regulation of epithelial cell proliferation
negative regulation of peptidyl-tyrosine phosphorylation
convergent extension involved in axis elongation
bone morphogenesis
sclerotome development
negative regulation of dermatome development
hematopoietic stem cell proliferation
cellular response to X-ray
negative regulation of canonical Wnt signaling pathway
planar cell polarity pathway involved in neural tube closure
Wnt signaling pathway involved in somitogenesis
positive regulation of canonical Wnt signaling pathway
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
regulation of dopaminergic neuron differentiation
midbrain morphogenesis
regulation of stem cell division
negative regulation of planar cell polarity pathway involved in axis elongation

Function(s)

fibronectin binding
G-protein coupled receptor activity
integrin binding
Wnt-protein binding
Wnt-activated receptor activity
receptor agonist activity
endopeptidase activator activity