122151

• Gene Symbol: DNA2
• Gene Name: DNA replication helicase/nuclease 2
• Gene Aliases: DNA2L, hDNA2
• Chromosome Location: Chr.10: 68414064 - 68472521 on Build GRCh38
• UniGene ID: Hs.532446
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DNA2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001080449.2	NP_001073918.2	2	236
	NR_102264.1		3	216
	XM_006717680.3	XP_006717743.1	3	616
GenBank mRNA	AK307939.1	-	2	203
	AK308333.1	-	2	236
	BC063664.1	-	2	149
	BC111740.1	-	3	216	40038149
	D42046.1	-	2	178
	DC404138.1	-	2	237

More Information

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
telomere maintenance via recombination
telomere maintenance
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
DNA replication
mitochondrial DNA replication
base-excision repair
DNA duplex unwinding
DNA replication, Okazaki fragment processing
DNA replication, removal of RNA primer
mitochondrial DNA repair
positive regulation of DNA replication
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
mitotic telomere maintenance via semi-conservative replication

Function(s)

DNA binding
DNA helicase activity
helicase activity
nuclease activity
protein binding
ATP binding
ATPase activity
site-specific endodeoxyribonuclease activity, specific for altered base
5'-flap endonuclease activity
5'-3' DNA helicase activity
single-stranded DNA-dependent ATPase activity
metal ion binding
4 iron, 4 sulfur cluster binding