122390

• Gene Symbol: APC
• Gene Name: APC, WNT signaling pathway regulator
• Gene Aliases: BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
• Chromosome Location: Chr.5: 112707505 - 112846239 on Build GRCh38
• UniGene ID: Hs.158932
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: APC
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000038.5	NP_000029.2	4	457
	NM_001127510.2	NP_001120982.1	5	565
	NM_001127511.2	NP_001120983.2	3	615
GenBank mRNA	AB210001.1	-	5	529
	AK289567.1	-	4	519
	AK294544.1	-	3	599
	BC056268.1	-	4	428
	DA795663.1	-	4	457
	M73548.1	-	3	410
	M74088.1	-	3	390

More Information

Gene Ontology Categories:

Process(es)

mitotic cytokinesis
cell fate specification
protein complex assembly
cellular component disassembly involved in execution phase of apoptosis
cellular response to DNA damage stimulus
negative regulation of microtubule depolymerization
cell cycle arrest
mitotic spindle assembly checkpoint
cell adhesion
establishment or maintenance of cell polarity
pattern specification process
negative regulation of cell proliferation
Wnt signaling pathway
cell migration
positive regulation of cell migration
pancreas development
neuron projection development
positive regulation of pseudopodium assembly
regulation of microtubule-based process
response to drug
positive regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of cell differentiation
positive regulation of protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase activity
regulation of attachment of spindle microtubules to kinetochore
canonical Wnt signaling pathway
bicellular tight junction assembly
negative regulation of canonical Wnt signaling pathway
response to alcohol
beta-catenin destruction complex assembly
beta-catenin destruction complex disassembly
cellular response to nerve growth factor stimulus
regulation of glutamate metabolic process

Function(s)

protein binding
beta-catenin binding
microtubule binding
protein kinase regulator activity
protein kinase binding
protein complex binding
gamma-catenin binding
cadherin binding
microtubule plus-end binding