123448

• Gene Symbol: E2F8
• Gene Name: E2F transcription factor 8
• Gene Aliases: E2F-8
• Chromosome Location: Chr.11: 19224063 - 19241655 on Build GRCh38
• UniGene ID: Hs.523526
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: E2F8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256371.1	NP_001243300.1	6	1131
	NM_001256372.1	NP_001243301.1	6	1076
	NM_024680.3	NP_078956.2	6	1330
	XM_011520367.1	XP_011518669.1	5	1017
GenBank mRNA	AK055206.1	-	6	1272
	AK292688.1	-	6	1041
	BC126400.1	-	6	1321	8992116
	BC126402.1	-	6	1321	8992118
	BU164108.1	-	4	680

More Information

Panther Classification:

Molecular Function -

RNA metabolism protein, nucleic acid metabolism protein, general transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
placenta development
sprouting angiogenesis
transcription, DNA-templated
cell proliferation
negative regulation of cytokinesis
positive regulation of DNA endoreduplication
cell cycle comprising mitosis without cytokinesis
positive regulation of transcription from RNA polymerase II promoter
trophoblast giant cell differentiation
chorionic trophoblast cell differentiation
hepatocyte differentiation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
protein homodimerization activity