124190

• Gene Symbol: SYVN1
• Gene Name: synoviolin 1
• Gene Aliases: DER3, HRD1
• Chromosome Location: Chr.11: 65127279 - 65135178 on Build GRCh38
• UniGene ID: Hs.75859
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SYVN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_032431.2	NP_115807.1	4, 5	468
	NM_172230.2	NP_757385.1	4, 5	468
	XM_011545303.2	XP_011543605.1	4, 5	1316
GenBank mRNA	AB085847.1	-	3, 4	374
	AF317634.1	-	3, 4	374
	AK074148.1	-	4, 5	423
	AK126912.1	-	4, 5	469
	AL834262.1	-	4, 5	468
	BC030530.1	-	4, 5	409	5211742

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001100739, XM_006230852, BC166727.
This siRNA also targets the following transcripts in Mouse: NM_001164709, NM_028769, AK004688, BC042199, BC046829, and others.

Gene Ontology Categories:

Process(es)

protein ubiquitination
protein N-linked glycosylation via asparagine
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
retrograde protein transport, ER to cytosol
IRE1-mediated unfolded protein response
ERAD pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
protein stabilization
protein K48-linked ubiquitination
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
endoplasmic reticulum mannose trimming

Function(s)

protein binding
zinc ion binding
ligase activity
unfolded protein binding
chaperone binding
ATPase binding
ubiquitin protein ligase activity
ubiquitin protein ligase activity involved in ERAD pathway
ubiquitin-specific protease binding