12488

• Gene Symbol: SMARCB1
• Gene Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
• Gene Aliases: BAF47, CSS3, INI1, MRD15, PPP1R144, RDT, RTPS1, SNF5, SNF5L1, SWNTS1, Sfh1p, Snr1, hSNFS
• Chromosome Location: Chr.22: 23786931 - 23834518 on Build GRCh38
• UniGene ID: Hs.534350
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SMARCB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001007468.2	NP_001007469.1	2	368
	NM_001317946.1	NP_001304875.1	2	368
	NM_003073.4	NP_003064.2	2	368
	XM_011530345.2	XP_011528647.1	2	337
GenBank mRNA	AB017523.1	-	2	129
	AJ011737.1	-	2	276
	AJ011738.1	-	2	276
	AK021419.1	-	2	301
	AK024025.1	-	2	336
	AK299411.1	-	2	298
	AK303620.1	-	2	319
	AL389878.1	-	2	178
	AU143041.1	-	2	336
	BC117114.1	-	2	184	40125665
	BC143667.1	-	2	184	9052181
	BG705851.1	-	2	341
	CR456581.1	-	2	182
	HY013730.1	-	2	370

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001025728, XM_006256318, XM_008773843, XM_008773844, BC099195, and others.
This siRNA also targets the following transcripts in Mouse: NM_001161853, NM_011418, AJ011740, AB017343, BC025163, and others.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

blastocyst hatching
DNA repair
nucleosome disassembly
chromatin remodeling
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell cycle
nervous system development
negative regulation of cell proliferation
DNA integration
covalent chromatin modification
cell differentiation
single stranded viral RNA replication via double stranded DNA intermediate
ATP-dependent chromatin remodeling
positive regulation by host of viral transcription
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of histone H4 acetylation
negative regulation of histone H3-K9 dimethylation
negative regulation of histone H3-K9 trimethylation
positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
positive regulation of glucose mediated signaling pathway
positive regulation of histone H3-K9 acetylation
regulation of histone H4-K16 acetylation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase I CORE element sequence-specific DNA binding
p53 binding
DNA binding
transcription coactivator activity
protein binding
Tat protein binding
nucleosomal DNA binding