12666

• Gene Symbol: SNAI2
• Gene Name: snail family transcriptional repressor 2
• Gene Aliases: SLUG, SLUGH1, SNAIL2, WS2D
• Chromosome Location: Chr.8: 48917677 - 48921440 on Build GRCh38
• UniGene ID: Hs.360174
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SNAI2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003068.4	NP_003059.1	2	787
GenBank mRNA	AK223368.1	-	2	776
	AK312661.1	-	2	776
	BC014890.1	-	2	764	3908245
	BC015895.1	-	2	744	3911047

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011415, AK133968, U97059, BC062164, U79550.

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
osteoblast differentiation
epithelial to mesenchymal transition
epithelial to mesenchymal transition involved in endocardial cushion formation
cell migration involved in endocardial cushion formation
transcription, DNA-templated
negative regulation of cell adhesion involved in substrate-bound cell migration
Notch signaling pathway
sensory perception of sound
negative regulation of keratinocyte proliferation
negative regulation of vitamin D biosynthetic process
neural crest cell development
positive regulation of cell migration
negative regulation of chondrocyte differentiation
regulation of chemokine production
negative regulation of cell adhesion mediated by integrin
positive regulation of histone acetylation
negative regulation of catenin import into nucleus
desmosome disassembly
pigmentation
negative regulation of DNA damage response, signal transduction by p53 class mediator
cellular response to fibroblast growth factor stimulus
positive regulation of fat cell differentiation
regulation of osteoblast differentiation
white fat cell differentiation
palate development
canonical Wnt signaling pathway
epithelium development
cartilage morphogenesis
regulation of branching involved in salivary gland morphogenesis
negative regulation of vitamin D receptor signaling pathway
cellular response to epidermal growth factor stimulus
cellular response to ionizing radiation
negative regulation of canonical Wnt signaling pathway
negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of stem cell proliferation
regulation of bicellular tight junction assembly
negative regulation of anoikis
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
sequence-specific DNA binding
metal ion binding