126754

• Gene Symbol: EIF2AK1
• Gene Name: eukaryotic translation initiation factor 2 alpha kinase 1
• Gene Aliases: HCR, HRI
• Chromosome Location: Chr.7: 6022247 - 6059229 on Build GRCh38
• UniGene ID: Hs.520205
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EIF2AK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001134335.1	NP_001127807.1	5	680
	NM_014413.3	NP_055228.2	5	680
GenBank mRNA	AB037790.1	-	5	605
	AF100784.1	-	5	569
	AF147094.1	-	5	615
	AF183414.1	-	5	567
	AF255050.1	-	5	625
	AK075192.1	-	5	608
	AK290327.1	-	5	613
	AK295712.1	-	4	481
	AL136563.1	-	5	585
	AL834494.1	-	5	585
	BC006524.2	-	5	612	2989989

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

acute inflammatory response
phagocytosis
response to stress
negative regulation of cell proliferation
response to external stimulus
regulation of translational initiation by eIF2 alpha phosphorylation
regulation of eIF2 alpha phosphorylation by heme
macrophage differentiation
negative regulation of translational initiation by iron
protoporphyrinogen IX metabolic process
protein autophosphorylation
negative regulation of hemoglobin biosynthetic process
iron ion homeostasis

Function(s)

eukaryotic translation initiation factor 2alpha kinase activity
ATP binding
heme binding
protein homodimerization activity