12740

• Gene Symbol: TDG
• Gene Name: thymine DNA glycosylase
• Gene Aliases: hTDG
• Chromosome Location: Chr.12: 103965815 - 103988878 on Build GRCh38
• UniGene ID: Hs.584809
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TDG
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003211.4	NP_003202.3	2, 3	399
	XM_005269125.1	XP_005269182.1	2, 3	259
	XM_011538714.1	XP_011537016.1	1, 2	229
	XM_011538715.1	XP_011537017.1	1, 2	229
GenBank mRNA	AK299832.1	-	2, 3	311
	AK303631.1	-	1, 2	226
	AK311673.1	-	1, 2	229
	AK313234.1	-	2, 3	342
	AL710869.1	-	3, 4	551
	BC019925.1	-	2, 3	353
	BC037557.1	-	2, 3	352	5184772
	BC104477.1	-	2, 3	315
	CB047650.1	-	1, 2	210
	DB162106.1	-	2, 3	400

More Information

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
base-excision repair
base-excision repair, AP site formation
mismatch repair
transcription, DNA-templated
embryo development
covalent chromatin modification
protein sumoylation
negative regulation of protein binding
oxidative DNA demethylation
negative regulation of chromatin binding
regulation of gene expression, epigenetic
depyrimidination
DNA demethylation

Function(s)

RNA polymerase II transcription cofactor activity
damaged DNA binding
double-stranded DNA binding
uracil DNA N-glycosylase activity
protein kinase C binding
protein binding
pyrimidine-specific mismatch base pair DNA N-glycosylase activity
DNA N-glycosylase activity
mismatched DNA binding
SUMO binding
protein homodimerization activity
structure-specific DNA binding