128935

Gene Symbol:

EGLN2 RAB4B-EGLN2

Gene Name:

egl-9 family hypoxia inducible factor 2

RAB4B-EGLN2 readthrough (NMD candidate)

Gene Aliases:

EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1

RERT-lncRNA

Chromosome Location:

Chr.19: 40799143 - 40808441 on Build GRCh38

Chromosome Location:

Chr.19: 40778219 - 40808441 on Build GRCh38

UniGene ID:

Hs.515417

Hs.631539

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: EGLN2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053046.3	NP_444274.1	5, 6	1616
	NM_080732.3	NP_542770.2	5, 6	1526
GenBank mRNA	AJ310544.1	-	4, 5	1468
	AK025396.1	-	1, 2	47
	AK026863.1	-	2, 3	771
	AK074408.1	-	5, 6	1455
	AK098182.1	-	4, 5	2200
	AL133009.1	-	2, 3	3274
	AL832506.1	-	5, 6	1482
	AY040565.1	-	4, 5	1460
	BC001723.1	-	5, 6	1429
	BC036051.1	-	5, 6	1530	5270945

Gene Symbol: RAB4B-EGLN2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_037791.1		11, 12	2220
GenBank mRNA	AK291385.1	-	11, 12	2168

More Information

Gene Ontology Categories:

Process(es)

regulation of cell growth
response to hypoxia
peptidyl-proline hydroxylation to 4-hydroxy-L-proline
intracellular estrogen receptor signaling pathway
regulation of neuron apoptotic process
cell redox homeostasis
positive regulation of protein catabolic process
oxidation-reduction process
regulation of transcription from RNA polymerase II promoter in response to hypoxia

Function(s)

protein binding
ferrous iron binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
oxygen sensor activity
L-ascorbic acid binding
peptidyl-proline 4-dioxygenase activity