13110

• Gene Symbol: EZR
• Gene Name: ezrin
• Gene Aliases: CVIL, CVL, HEL-S-105, VIL2
• Chromosome Location: Chr.6: 158765741 - 158819424 on Build GRCh38
• UniGene ID: Hs.487027
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EZR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001111077.1	NP_001104547.1	4	349
	NM_003379.4	NP_003370.2	3	383
GenBank mRNA	AK296738.1	-	4	312
	AK312597.1	-	4	293
	AL162086.1	-	4	301
	BC013903.2	-	3	300	2959399
	BC068458.1	-	3	309	4819793
	DA754543.1	-	4	349
	FJ224318.1	-	3	285
	J05021.1	-	3	244
	X51521.1	-	3	285

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019357, AF450298, BC081958, AY428869.
This siRNA also targets the following transcripts in Mouse: NM_009510, BC048181, AK168410, X60671, AK135353, and others.

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
intestinal D-glucose absorption
sphingosine-1-phosphate signaling pathway
cytoskeletal anchoring at plasma membrane
leukocyte cell-cell adhesion
axon guidance
regulation of cell shape
regulation of cell size
positive regulation of gene expression
protein kinase A signaling
gland morphogenesis
membrane to membrane docking
microvillus assembly
astral microtubule organization
actin cytoskeleton reorganization
receptor internalization
regulation of microvillus length
regulation of actin cytoskeleton organization
cellular protein complex localization
positive regulation of multicellular organism growth
cortical microtubule organization
establishment of epithelial cell apical/basal polarity
filopodium assembly
phosphatidylinositol-mediated signaling
positive regulation of protein secretion
negative regulation of T cell receptor signaling pathway
actin filament bundle assembly
establishment of centrosome localization
establishment of endothelial barrier
negative regulation of ERK1 and ERK2 cascade
cellular response to cAMP
protein localization to cell cortex
establishment of protein localization to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
negative regulation of interleukin-2 secretion
regulation of NIK/NF-kappaB signaling
regulation of organelle assembly
terminal web assembly
positive regulation of protein localization to early endosome
positive regulation of cellular protein catabolic process
negative regulation of p38MAPK cascade
positive regulation of early endosome to late endosome transport

Function(s)

actin binding
protein binding
microtubule binding
protein domain specific binding
protein kinase A catalytic subunit binding
protein kinase A regulatory subunit binding
S100 protein binding
poly(A) RNA binding
cell adhesion molecule binding
actin filament binding
ATPase binding
cadherin binding involved in cell-cell adhesion