132365

• Gene Symbol: EDEM2
• Gene Name: ER degradation enhancing alpha-mannosidase like protein 2
• Gene Aliases: C20orf31, C20orf49, bA4204.1
• Chromosome Location: Chr.20: 35115357 - 35147358 on Build GRCh38
• UniGene ID: Hs.720177
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EDEM2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001145025.1	NP_001138497.1	10	1505
	NM_018217.2	NP_060687.2	11	1616
	NR_026728.1		10	1832
GenBank mRNA	AF086313.1	-	1	247
	AK001645.1	-	11	1598
	AK023931.1	-	11	1586
	AK096016.1	-	9	1526
	AK293583.1	-	10	1487
	AK298794.1	-	10	1574
	AK300212.1	-	10	1460
	AK303816.1	-	9	1258
	AY007088.1	-	8	1184
	AY358580.1	-	10	1466
	BC001371.2	-	11	1583	3051376
	BC016184.1	-	11	1557	4860424
	BU188881.1	-	1	265
	CR457266.1	-	11	1516

More Information

Gene Ontology Categories:

Process(es)

N-glycan processing
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
trimming of terminal mannose on B branch
glycoprotein ERAD pathway
positive regulation of retrograde protein transport, ER to cytosol
endoplasmic reticulum mannose trimming
mannose trimming involved in glycoprotein ERAD pathway

Function(s)

glycoprotein binding
alpha-mannosidase activity
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
calcium ion binding