132907

• Gene Symbol: METTL3
• Gene Name: methyltransferase like 3
• Gene Aliases: IME4, M6A, MT-A70, Spo8
• Chromosome Location: Chr.14: 21498131 - 21511375 on Build GRCh38
• UniGene ID: Hs.168799
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: METTL3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019852.4	NP_062826.2	3	550
	XM_006720206.3	XP_006720269.1	3	530
	XM_011536968.1	XP_011535270.1	3	545
GenBank mRNA	AK000222.1	-	3	473
	AK093509.1	-	1	332
	AK097873.1	-	2	1358
	AK098655.1	-	2	246
	AK300289.1	-	3	515
	AK304251.1	-	3	515
	BC001650.2	-	3	484	2821235
	BC003031.1	-	3	484	2821235
	BC052244.1	-	3	434	6081642
	DC295053.1	-	3	550

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001024794, XM_008770555, BC097400.

Panther Classification:

Molecular Function -

RNA metabolism protein, RNA methyltransferase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
RNA methylation
adenosine to inosine editing
mRNA processing
circadian rhythm
gene expression
stem cell population maintenance
primary miRNA processing
mRNA destabilization
mRNA methylation
positive regulation of cap-independent translational initiation
primary miRNA methylation

Function(s)

mRNA binding
RNA methyltransferase activity
mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
protein heterodimerization activity
S-adenosyl-L-methionine binding