133090

• Gene Symbol: TIGAR
• Gene Name: TP53 induced glycolysis regulatory phosphatase
• Gene Aliases: C12orf5, FR2BP
• Chromosome Location: Chr.12: 4321193 - 4360028 on Build GRCh38
• UniGene ID: Hs.504545
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TIGAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_020375.2	NP_065108.1	6	1160
GenBank mRNA	AJ272206.1	-	6	1148
	AY425618.1	-	6	1119
	BC012340.1	-	6	1119	4576725

More Information

Panther Classification:

Molecular Function -

phosphatase

Gene Ontology Categories:

Process(es)

response to ischemia
fructose 2,6-bisphosphate metabolic process
autophagy
apoptotic process
cellular response to DNA damage stimulus
response to xenobiotic stimulus
response to gamma radiation
positive regulation of cardiac muscle cell apoptotic process
dephosphorylation
fructose 1,6-bisphosphate metabolic process
negative regulation of programmed cell death
regulation of pentose-phosphate shunt
positive regulation of DNA repair
negative regulation of glycolytic process
intestinal epithelial cell development
cellular response to cobalt ion
cellular response to hypoxia
negative regulation of neuron death
negative regulation of macromitophagy
regulation of response to DNA damage checkpoint signaling
positive regulation of hexokinase activity
negative regulation of glucose catabolic process to lactate via pyruvate
negative regulation of reactive oxygen species metabolic process

Function(s)

bisphosphoglycerate 2-phosphatase activity
fructose-2,6-bisphosphate 2-phosphatase activity
protein binding