133175

• Gene Symbol: PELI1
• Gene Name: pellino E3 ubiquitin protein ligase 1
• Gene Aliases: -
• Chromosome Location: Chr.2: 64092652 - 64144471 on Build GRCh38
• UniGene ID: Hs.7886
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PELI1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_020651.3	NP_065702.2	4	687
	XM_005264437.3	XP_005264494.1	3	506
	XM_011532994.2	XP_011531296.1	4	1346
	XM_011532996.2	XP_011531298.1	4	2105
	XM_011532997.2	XP_011531299.1	3	506
	XM_017004520.1	XP_016860009.1	5	821
	XM_017004521.1	XP_016860010.1	5	680
GenBank mRNA	AF300987.1	-	3	242
	AF302505.1	-	3	4265
	AJ278859.1	-	3	227
	AK312441.1	-	4	636
	AY364257.1	-	3	227
	BC050019.1	-	4	641	5296990
	BC050533.1	-	4	623
	BC063611.1	-	4	615	4992160

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_023324, AF302503, AK029586, AK152997, AK167525, and others.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

positive regulation of cytokine production
Toll signaling pathway
positive regulation of B cell proliferation
positive regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
response to lipopolysaccharide
positive regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
negative regulation of T cell proliferation
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to dsRNA
protein K48-linked ubiquitination

Function(s)

protein binding
ligase activity
ubiquitin-ubiquitin ligase activity