1332

• Gene Symbol: BCR
• Gene Name: BCR, RhoGEF and GTPase activating protein
• Gene Aliases: ALL, BCR1, CML, D22S11, D22S662, PHL
• Chromosome Location: Chr.22: 23180365 - 23318037 on Build GRCh38
• UniGene ID: Hs.517461
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BCR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004327.3	NP_004318.3	1	1174
	NM_021574.2	NP_067585.2	1	1174
GenBank mRNA	AB209991.1	-	1	923
	BC066122.1	-	1	1005
	EU216058.1	-	1	578
	EU216059.1	-	1	578
	EU216061.1	-	1	578
	EU216062.1	-	1	578
	EU216063.1	-	1	578
	EU216064.1	-	1	578
	EU216067.1	-	1	578
	EU216069.1	-	1	578
	EU216070.1	-	1	578
	X02596.1	-	1	1066
	X06418.1	-		621
	Y00661.1	-	1	1174

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_228091.
This siRNA also targets the following transcripts in Mouse: NM_001081412.

Panther Classification:

Molecular Function -

G-protein modulator

Gene Ontology Categories:

Process(es)

negative regulation of cellular extravasation
protein phosphorylation
signal transduction
brain development
peptidyl-tyrosine phosphorylation
actin cytoskeleton organization
response to lipopolysaccharide
regulation of Rho protein signal transduction
intracellular signal transduction
inner ear morphogenesis
regulation of vascular permeability
negative regulation of neutrophil degranulation
positive regulation of GTPase activity
protein autophosphorylation
platelet-derived growth factor receptor signaling pathway
negative regulation of inflammatory response
positive regulation of phagocytosis
neuromuscular process controlling balance
regulation of small GTPase mediated signal transduction
regulation of cell cycle
negative regulation of blood vessel remodeling

Function(s)

protein serine/threonine kinase activity
protein tyrosine kinase activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding
ATP binding
kinase activity
enzyme binding