133261

• Gene Symbol: MKL1
• Gene Name: megakaryoblastic leukemia (translocation) 1
• Gene Aliases: BSAC, MAL, MRTF-A
• Chromosome Location: Chr.22: 40410281 - 40636719 on Build GRCh38
• UniGene ID: Hs.654688
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MKL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001282660.1	NP_001269589.1	9	1356
	NM_001282661.1	NP_001269590.1	11	1618
	NM_001282662.1	NP_001269591.1	12	1768
	NM_001318139.1	NP_001305068.1	10	1493
	NM_020831.4	NP_065882.1	12	1768
	XM_005261692.1	XP_005261749.1	11	1573
	XM_005261694.1	XP_005261751.1	11	1663
	XM_011530283.1	XP_011528585.1	13	1876
	XM_011530285.1	XP_011528587.1	13	1787
	XM_011530287.1	XP_011528589.1	5	755
	XM_017028888.1	XP_016884377.1	12	1851
	XM_017028889.1	XP_016884378.1	8	2851
GenBank mRNA	AB037859.2	-	12	1740
	AF368061.1	-	12	1693
	AJ297257.1	-	9	1350
	AJ297258.1	-	12	1750
	AL713710.1	-	4	563
	BC115039.1	-	12	1734	5551767
	BC139730.1	-	10	1407
	CR456522.1	-	9	1167
	HG764171.1	-	10	1493

More Information

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
positive regulation of transcription via serum response element binding
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of transcription from RNA polymerase II promoter
smooth muscle cell differentiation
negative regulation of apoptotic signaling pathway

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II transcription coactivator activity
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
actin binding
actin monomer binding
protein binding
leucine zipper domain binding