133297

• Gene Symbol: ALS2
• Gene Name: ALS2, alsin Rho guanine nucleotide exchange factor
• Gene Aliases: ALS2CR6, ALSJ, IAHSP, PLSJ
• Chromosome Location: Chr.2: 201700263 - 201781172 on Build GRCh38
• UniGene ID: Hs.471096
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ALS2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001135745.1	NP_001129217.1	4	777
	NM_020919.3	NP_065970.2	4	777
	XM_006712654.2	XP_006712717.1	4	1354
	XM_011511530.2	XP_011509832.1	3	489
	XM_017004569.1	XP_016860058.1	3	481
	XM_017004570.1	XP_016860059.1	3	481
	XM_017004571.1	XP_016860060.1	3	481
GenBank mRNA	AB046783.2	-	3	498
	AB053305.1	-	4	544
	AB053306.1	-	4	544
	AF391100.1	-	4	544
	AK023024.1	-	4	544
	AK291029.1	-	4	561
	BC029174.1	-	4	547
	BC071576.1	-	4	539	30347073
	KU178735.1	-	3	421
	KU178736.1	-	3	421

More Information

Gene Ontology Categories:

Process(es)

behavioral fear response
in utero embryonic development
receptor recycling
response to oxidative stress
endosome organization
axonogenesis
neuromuscular junction development
locomotory behavior
protein localization
cell death
vesicle organization
endosomal transport
Rac protein signal transduction
positive regulation of Rac protein signal transduction
regulation of Rho protein signal transduction
synaptic transmission, glutamatergic
positive regulation of GTPase activity
positive regulation of protein kinase activity
neuron projection morphogenesis
regulation of endosome size
positive regulation of protein serine/threonine kinase activity

Function(s)

guanyl-nucleotide exchange factor activity
Ran guanyl-nucleotide exchange factor activity
protein binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
Rac guanyl-nucleotide exchange factor activity
protein homodimerization activity
protein serine/threonine kinase activator activity